#Question id: 12396
#Unit 6. System Physiology – Plant
#Question id: 5119
#Unit 5. Developmental Biology
when the presumptive eye region from a gastrula is grafted into the trunk region of another neurula, it develops to somitic tissue; whereas transplant from eye region of later stage neurula develops as an eye-like structure in host embryo. Which statement describes the results best?
#Question id: 8861
#Unit 9. Diversity of Life Forms
Which of the following is true of members of the phylum Cnidaria?
#Question id: 1044
#Unit 4. Cell Communication and Cell Signaling
Are all fungi detrimental (bad) for other organisms?
#Question id: 1364
#Unit 4. Cell Communication and Cell Signaling
In mice engineered to overexpress the syndecan-1 gene in the hypothalamic region of the brain and other tissues, normal control of feeding by antisatiety peptides is disrupted, and the animals overeat and become obese. Other studies have shown that syndecan-3 may also be involved in the regulation of feeding behavior. Given the following information, which of these outcomes might you expect in experimentally manipulated mice?
I. Hypothalmic expression of syndecan-3 is increased by fasting.
II. Syndecan-3 knockout mice are resistant to diet-induced obesity.
III. Heparinase can cleave syndecan-3 to release heparin sulfate GAG chains that may suppress the activity of antisatiety peptides and feeding behavior.
Following statements are:
A. Overexpression of heparinase in mice with normal levels of syndecan-3 would result in resistance to diet-induced obesity.
B. In mice with normal levels of syndecan-3, fasting followed by free access to a high-fat diet would lead to resistance to diet-induced obesity.
C. Lack of heparinase in mice with normal levels of syndecan-3 would result in animals that overeat and become obese.
D. Overexpression of heparinase in syndecan-3 knockout mice would reverse the resistance to diet-induced obesity.
Which of the following combination is correct?