Choose correct statements about ‘Protein Disulfide Isomerase’ in protein folding

A. Oxidized PDI catalyzes the rearrangement of a polypeptide’s non-native disulfide bonds via disulfide interchange reactions to yield native disulfide bonds.

B. Reduced PDI catalyzes the initial formation of a polypeptide’s disulfide bonds through the formation of a mixed disulfide.

C. Protein disulfide isomerase contains the conserved active site motif of Cys-Xaa-Xaa-Cys found in thioredoxin and shares a similar role to the Dsb family of proteins found in E. coli.

D. Under more reducing conditions with thiols in the active site the enzyme reshuffles disulfides (isomerase) in target proteins.

#Question id: 5252

#Unit 8. Inheritance Biology

Which type(s) of genetic transfer lead to incorporation of new DNA into the bacterial chromosome?

I. Conjugation mediated by F factor

II. Hfr mediated conjugation

III. Transduction

IV. Transformation

#Question id: 5253

#Unit 8. Inheritance Biology

In a hypothetical situation, the genes for sex pilus construction and for tetracycline resistance are located together on the same plasmid within a particular bacterium. If this bacterium readily performs conjugation involving a copy of this plasmid, then the resultshould be

#Question id: 5254

#Unit 5. Developmental Biology

Following signal transduction pathways can be grouped into several basic types, based on the sequence of intracellular events.

According to above figure, which of the following correctly represents the basic concepts of all signalling pathway?

#Question id: 5255

#Unit 8. Inheritance Biology

Which of the following is a structure that permits conjugation to occur?

#Question id: 5256

#Unit 8. Inheritance Biology

If the experimental population of E. coli lacks an F factor or F plasmid, and if bacteriophage are excluded from the bacterial cultures, then which of these is a means by which beneficial mutations might be transmitted horizontally to other E. coli cells?

#Question id: 5257

#Unit 8. Inheritance Biology

Which term is least closely associated with the others?