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TLS Online TPP Program
#Question id: 15780
#Unit 5. Developmental Biology
In drosophila, the somatic cells of the hub are able to regulate stem cell proliferation by secreting the paracrine factor Unpaired onto the cells attached to them. Unpaired activates the JAK-STAT pathway in the adjacent germ stem cells to specify their self-renewal. Those cells that are distant from the paracrine factor cannot receive this signal, they begin their differentiation into the sperm cell lineage. This means hub cells act as
TLS Online TPP Program
#Question id: 15781
#Unit 5. Developmental Biology
Chemical regulation of stem cells takes the form of secreted proteins from surrounding cells that influence stem cell states and progenitor differentiation through endocrine, paracrine, or juxtacrine mechanisms. These signaling factors:
TLS Online TPP Program
#Question id: 15782
#Unit 5. Developmental Biology
Adult cells may be reprogrammed to gain pluripotency by modifying the genes namely
TLS Online TPP Program
#Question id: 15783
#Unit 5. Developmental Biology
During the formation of induced pluripotent stem cell, what is the function of Klf-4?
TLS Online TPP Program
#Question id: 15784
#Unit 5. Developmental Biology
During the formation of induced pluripotent stem cell, what is the function of C-myc?
TLS Online TPP Program
#Question id: 15785
#Unit 5. Developmental Biology
During the formation of induced pluripotent stem cell, what is the function of Sox2 and Oct4?
A. Established pluripotency and blocked differentiation.
B. Opened up chromatin
C. Activation of Nanog.
D. Promotes cell growth and proliferation