A 32-year-old man complains of frequent urination. He is overweight (280 lb, 5 ft 10 in tall), and after measuring the 24-hr creatinine clearance, you estimate his GFR to be 150 ml/min. His plasma glucose is 300 mg/dL. Assuming that his renal transport maximum for glucose is normal, as shown in the figure above, what would be this patient’s approximate rate of urinary glucose excretion?

#Question id: 2806

#Unit 2. Cellular Organization

Pseudogenes arise from the action of an enzyme

#Question id: 2807

#Unit 2. Cellular Organization

Huntington’s disease is an example of

a. an autosomal recessive disorder.    b. an autosomal dominant disorder.

c. a sex linked recessive disorder.      d. a sex linked dominant disorder.

#Question id: 2808

#Unit 2. Cellular Organization

A microsatellite is a type of polymorphism that

a. results from the change of a single nucleotide.

b. changes the recognition sequence for a restriction enzyme.

c. results from a variable number of repetitive sequences.

d. results from a chromosomal inversion.

#Question id: 2809

#Unit 2. Cellular Organization

In the human genome, one centimorgan or a 1 percent recombination frequency represents, on average, a distance of about

#Question id: 2810

#Unit 2. Cellular Organization

Which of the following steps is required to generate a knockout mouse?

a. microinjection of DNA into the pronucleus of a fertilized mouse egg

b. introduction of DNA into mouse embryonic stem cells

c. selection for cells containing the gene targeted insertion

d. expression of Cre protein during embryonic development

#Question id: 2811

#Unit 2. Cellular Organization

RNA interference is a method for inhibiting the function of specific genes using

a. single-stranded DNA.                     

b. double-stranded DNA.

c. single-stranded RNA.                     

d. double-stranded RNA.