TLS Online TPP Program

#Question id: 12483


ATM and ATR are protein kinases that become activated following specific types of DNA damage. 
A. ATM becomes activated in response to double‐strand breaks, which are detected by the MRN protein complex. 
B. ATR becomes activated by protein‐coated ssDNA that forms when replication forks become stalled or the DNA is being repaired after various types of damage.
C. ATR phosphorylates and activates the checkpoint kinase Chk2, which phosphorylates p53. D. ATM phosphorylates and activates the checkpoint kinase Chk1, which phosphorylates and inactivates the phosphatase Cdc25.
Which of the following combination is incorrect?

#Unit 2. Cellular Organization
  1. A and B
  2. B and C
  3. C and D
  4. A, B and D