The genomic DNA of an organism is digested with two restriction enzymes; one of the, PstI (CTGCA/G), while the other., MseI (T/TAA). This would generate the following 3 types of DNA fragments: 

(1) both ends cleaved by PstI (Pst-Pst), 

(2) both ends cleaved by MseI (Mse-Mse), and 

(3) one end generated by each of the two enzymes (Pst-Mse). 

the most frequent fragments in decreasing order,

TLS Online TPP Program

#Question id: 31076

#Unit 2. Cellular Organization

If Sic1 were inactivated following the phosphorylation of a single site, leading to a:

TLS Online TPP Program

#Question id: 31077

#Unit 2. Cellular Organization

Which of the following ubiquitin ligase protein  recognized the N-terminus of a geminin protein destruction box that leads to degradation by proteosome in late anaphase? 

TLS Online TPP Program

#Question id: 31078

#Unit 2. Cellular Organization

Which of the following activity prevents unloading of cohesins by Pds5-Wapl, thereby stabilizing the cohesins on chromosomes?

TLS Online TPP Program

#Question id: 31225

#Unit 2. Cellular Organization

The protein ring complexes that establish linkages between sister chromatids that is called as: 

TLS Online TPP Program

#Question id: 31226

#Unit 2. Cellular Organization

Cohesins associate with chromosomes by cohesin loading factors, known as:

TLS Online TPP Program

#Question id: 31227

#Unit 2. Cellular Organization

Fission yeast cells carrying a CDK1 mutation in which the tyrosine-15 residue is replaced by phenylalanine, what will be the result?

a) Shows larger than normal cells

b) Shows smaller than normal cells

c) allows the phosphorylation of phenylalanine and normal cell proliferation are seen

d) premature mitotic CDK activation and entry into mitosis