TLS Online TPP Program

#Question id: 13162


In the amoeba Dictyostelium discoideum, cAMP acts as an extracellular signalling molecule and binds to and signals via a G protein–coupled receptor; it is not a second messenger. Amoeba cells were transfected with genes encoding two fusion proteins: a Gα fused to cyan fluorescent protein (CFP), and a Gβ fused to yellow fluorescent protein (YFP). CFP normally fluoresces 490-nm light; YFP, 527-nm light. In which conditions fluorescence
energy transfer occur from CFP to YFP?

#Unit 4. Cell Communication and Cell Signaling
  1. If ligand binding occur it leads to association of the Gα and Gβγ subunits, then fluorescence energy transfer can occur.
  2. If ligand binding occur it leads to dissociation of the Gα and Gβγ subunits, then fluorescence energy transfer can occur.
  3. If ligand binding doesn’t occur (In resting state) it leads to dissociation of the Gα and Gβγ subunits, then fluorescence energy transfer can occur.
  4. If ligand binding doesn’t occur (In resting state) it leads to association of the Gα and Gβγ subunits, then fluorescence energy transfer can occur.
     
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TLS Online TPP Program

#Question id: 12380

#Unit 7. System Physiology – Animal

A person with normal body fluid volumes weighs 60 kg and has an extracellular fluid volume of approximately 12.8 L, a blood volume of 4.3 L, and a hematocrit of 0.4; 57% of his body weight is water. What is the approximate intracellular fluid volume?

TLS Online TPP Program

#Question id: 12381

#Unit 7. System Physiology – Animal

 A person with normal body fluid volumes weighs 60 kg and has an extracellular fluid volume of approximately 12.8 L, a blood volume of 4.3 L, and a hematocrit of 0.4; 57% of his body weight is water.
What is the approximate plasma volume?

TLS Online TPP Program

#Question id: 12382

#Unit 7. System Physiology – Animal

A person with normal body fluid volumes weighs 60 kg and has an extracellular fluid volume of approximately 12.8 L, a blood volume of 4.3 L, and a hematocrit of 0.4; 57% of his body weight is water.
What is the approximate interstitial fluid volume?

TLS Online TPP Program

#Question id: 12383

#Unit 7. System Physiology – Animal

Which of the following changes tends to increase urinary Ca++ excretion?

TLS Online TPP Program

#Question id: 12384

#Unit 7. System Physiology – Animal

To evaluate kidney function in a 45-year-old woman with type II diabetes, you ask her to collect her urine over 24 hours. She collects 3600 ml of urine in that period. The clinical laboratory returns the following results after analyzing the patient’s urine and plasma samples: plasma creatinine = 4 mg/dL, urine creatinine = 32 mg/dL, plasma potassium = 5 mmol/L, and urine potassium = 10 mmol/L.
What is this patient’s approximate GFR, assuming that she collected all her urine in the 24-hour period?

TLS Online TPP Program

#Question id: 12385

#Unit 7. System Physiology – Animal

To evaluate kidney function in a 45-year-old woman with type II diabetes, you ask her to collect her urine over 24 hours. She collects 3600 ml of urine in that period. The clinical laboratory returns the following results after analyzing the patient’s urine and plasma samples: plasma creatinine = 4 mg/dL, urine creatinine = 32 mg/dL, plasma potassium = 5 mmol/L, and urine potassium = 10 mmol/L.
What is the net renal tubular reabsorption rate of potassium in this patient?