TLS Online TPP Program

#Question id: 18774


The above Scatchard plots are based on repeated equilibrium dialyses with a constant concentration of antibody and varying concentration of ligand. In these plots, r equals moles of bound ligand/mole antibody and c is the concentration of free ligand, (Ka) is slope while intercept on x axis represent 

#Part-A Aptitude & General Biotechnology
  1. bound ligand
  2. total moles of ag - ab
  3. the number of binding sites per antibody molecule (n), or its valency
  4. Scatchard coefficient 
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TLS Online TPP Program

#Question id: 14135

#Part-A Aptitude & General Biotechnology

Which of the following statement is correct about PAM matrix? 

TLS Online TPP Program

#Question id: 14136

#Part-B Specialized Branches in Biotechnology

Which of the following statement is incorrect about global alignment? 
(A) Global alignment is based on the Needleman–Wunsch algorithm.
(B) In Global alignment algorithm, an optimal alignment is obtained over the entire lengths of the two sequences.
(C) It is only suitable for aligning two closely related sequences that are of the same length.
(D) GAP is a web-based pairwise global alignment program.

TLS Online TPP Program

#Question id: 14136

#Part-A Aptitude & General Biotechnology

Which of the following statement is incorrect about global alignment? 
(A) Global alignment is based on the Needleman–Wunsch algorithm.
(B) In Global alignment algorithm, an optimal alignment is obtained over the entire lengths of the two sequences.
(C) It is only suitable for aligning two closely related sequences that are of the same length.
(D) GAP is a web-based pairwise global alignment program.

TLS Online TPP Program

#Question id: 14137

#Part-B Specialized Branches in Biotechnology

Consider the following alignment of two DNA sequences:
                            AGTAAC
                            AA_ _AC

Assuming an affine gap scoring scheme of an identity matrix for substitution, a gap initiation penalty of 1 and a gap extension penalty of 0.1, the score of the alignment is _________

TLS Online TPP Program

#Question id: 14137

#Part-A Aptitude & General Biotechnology

Consider the following alignment of two DNA sequences:
                            AGTAAC
                            AA_ _AC

Assuming an affine gap scoring scheme of an identity matrix for substitution, a gap initiation penalty of 1 and a gap extension penalty of 0.1, the score of the alignment is _________

TLS Online TPP Program

#Question id: 14138

#Part-B Specialized Branches in Biotechnology

BLAST uses heuristics to align a query sequence with all sequences in a database. 
Reason(R): BLASTX uses protein sequences as queries to search against a protein sequence database.