#Question id: 882
#Part-A Aptitude & General Biotechnology
Choose correct statements about thermophilic proteins
I. The proteins found in thermophilic species are much more stable than their mesophilic counterparts.
II. All thermostable proteins have such a high incidence of salt bridges
III. the most important of which are an increased size of the protein’s hydrophobic core, an increased size of the interface between its domains and/or subunits, and a more tightly packed core as evidenced by a reduced surface-to-volume ratio.
IV. Several of these thermostable enzymes have a superabundance of salt bridges on their surfaces.
#Question id: 887
#Part-B Specialized Branches in Biotechnology
Polypeptides fold rapidly by a stepwise process, how does the polypeptide chain arrive at its native conformation?
#Question id: 887
#Part-A Aptitude & General Biotechnology
Polypeptides fold rapidly by a stepwise process, how does the polypeptide chain arrive at its native conformation?
#Question id: 891
#Part-B Specialized Branches in Biotechnology
The folding pathways of some proteins require two enzymes that catalyze isomerization reactions such as,
a) Peptide prolyl isomerase (PPI) catalyzes the elimination of folding intermediates with inappropriate disulfide cross-links
b) Protein disulfide isomerase (PDI) enzyme that catalyzes the interchange, or shuffling, of disulfide bonds until the bonds of the native conformation are formed
c) Peptide prolyl cis-trans isomerase (PPI) catalyzes the interconversion of the cis and trans isomers of Proline residue peptide bonds
d) Peptide prolyl isomerase (PPI) can be a fast step in the folding of proteins that contain some Pro peptide bonds in the cis conformation
Which of the following combinations is correct about protein folding pathways?
#Question id: 891
#Part-A Aptitude & General Biotechnology
The folding pathways of some proteins require two enzymes that catalyze isomerization reactions such as,
a) Peptide prolyl isomerase (PPI) catalyzes the elimination of folding intermediates with inappropriate disulfide cross-links
b) Protein disulfide isomerase (PDI) enzyme that catalyzes the interchange, or shuffling, of disulfide bonds until the bonds of the native conformation are formed
c) Peptide prolyl cis-trans isomerase (PPI) catalyzes the interconversion of the cis and trans isomers of Proline residue peptide bonds
d) Peptide prolyl isomerase (PPI) can be a fast step in the folding of proteins that contain some Pro peptide bonds in the cis conformation
Which of the following combinations is correct about protein folding pathways?
#Question id: 895
#Part-B Specialized Branches in Biotechnology
Which of the following is van’t Hoff plot equation?