TLS Online TPP Program

#Question id: 12497


In this pedigree A and B represent alleles at a marker locus closely linked to the disease locus. Affected individuals are shown as shaded. The disease status in III 1 is unknown. Which of the following is correct?

#Part-A Aptitude & General Biotechnology
  1. The probable pattern of inheritance shown by the disease in this family is autosomal recessive.
  2. If recombination does not occur the probability that III 1 will be affected if she has an AB marker genotype is 1.
  3. If recombination does not occur, the probability that III 1 will be affected if she has a BB marker genotype is 1.
  4. If the recombination fraction between the disease and marker loci equals 0.04, the probability that III 1 will be affected if she inherits an AB marker genotype equals 0.96.