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TLS Online TPP Program

#Question id: 12497

In this pedigree A and B represent alleles at a marker locus closely linked to the disease locus. Affected individuals are shown as shaded. The disease status in III 1 is unknown. Which of the following is correct?

#Part-A Aptitude & General Biotechnology
  1. The probable pattern of inheritance shown by the disease in this family is autosomal recessive.
  2. If recombination does not occur the probability that III 1 will be affected if she has an AB marker genotype is 1.
  3. If recombination does not occur, the probability that III 1 will be affected if she has a BB marker genotype is 1.
  4. If the recombination fraction between the disease and marker loci equals 0.04, the probability that III 1 will be affected if she inherits an AB marker genotype equals 0.96.

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TLS Online TPP Program

#Question id: 14137

#Part-A Aptitude & General Biotechnology

Consider the following alignment of two DNA sequences:
                            AGTAAC
                            AA_ _AC

Assuming an affine gap scoring scheme of an identity matrix for substitution, a gap initiation penalty of 1 and a gap extension penalty of 0.1, the score of the alignment is _________
TLS Online TPP Program

#Question id: 14138

#Part-B Specialized Branches in Biotechnology

BLAST uses heuristics to align a query sequence with all sequences in a database. 
Reason(R): BLASTX uses protein sequences as queries to search against a protein sequence database.
TLS Online TPP Program

#Question id: 14138

#Part-A Aptitude & General Biotechnology

BLAST uses heuristics to align a query sequence with all sequences in a database. 
Reason(R): BLASTX uses protein sequences as queries to search against a protein sequence database.
TLS Online TPP Program

#Question id: 14139

#Part-B Specialized Branches in Biotechnology

Which of the following statement is incorrect about sequence similarity and sequence identity? 
TLS Online TPP Program

#Question id: 14139

#Part-A Aptitude & General Biotechnology

Which of the following statement is incorrect about sequence similarity and sequence identity? 
TLS Online TPP Program

#Question id: 14140

#Part-B Specialized Branches in Biotechnology

In sequence alignment by BLAST, each word from query sequence is typically _______ residues for protein sequences and _______ residues for DNA sequences.