Class II MHC transcriptional activator called CIITA and another transcription factor called RFX, have both been shown to activate the promoter of class II MHC genes.

Defects in these transcription factors cause one form of bare lymphocyte syndrome.

TLS Online TPP Program

#Id: 10346

#Section 2: General Biology

T1 cells are mIgMhi, mIgD -/lo, CD21-, CD23-, CD24+, and CD93+. 

T2 cells differ from T1 cells in having higher levels of mIgD and in expressing CD21 and CD23. 

TLS Online TPP Program

#Id: 8156

#Section 3: Genetics, Cellular and Molecular Biology

Two different kinds of sorting signals:

Membrane cargo proteins carry cytoplasmic sorting signals

Soluble cargo proteins carry luminal sorting signals

TLS Online TPP Program

#Id: 7732

#Section 2: General Biology

Atoms are indivisible particles that can't be created or destroyed in a chemical reaction.

TLS Online TPP Program

#Id: 10343

#Section 2: General Biology

The heavy chain is then expressed on the cell surface in combination with the surrogate light chain, which is made up of VpreB and λ5. 

TLS Online TPP Program

#Id: 10317

#Section 2: General Biology

Cytotoxic T Cells target tumor cells

Most tumor cells, express MHC class I molecules on their surface, cytotoxic T cells can directly recognize them. 

cytotoxic T cells can result in killing of the tumor cells by two different mechanisms