The ER captures selected proteins from the cytosol as they are being synthesized. These are of two types:

Transmembrane proteins

Water-soluble proteins

#Id: 10330

#Section 2: General Biology

The idea behind CARs was to engineer the T-cell receptor to trigger activation of ZAP70 in response to the presence of a tumor-specific antigen rather than the MHC peptide complex. 

#Id: 10331

#Section 2: General Biology

#Id: 10332

#Section 2: General Biology

#Id: 10333

#Section 2: General Biology

#Id: 8981

#Section 3: Genetics, Cellular and Molecular Biology

Population genetics, applies the principles of transmission genetics to large groups of individuals. 

#Id: 8982

#Section 3: Genetics, Cellular and Molecular Biology