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Fingolimod—a Sphingosine-1-P Mimic Is an Oral Drug for Multiple Sclerosis

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The rate of addition of monomers is given by
rate constant kon (M–1 sec–1 )
The rate of loss is given by koff (sec–1)

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The Aurora kinase family members Aurora A and Aurora B play key roles in mitotic spindle formation and in ensuring that chromosomes attach correctly to the mitotic spindle so that they are segregated accurately during mitosis.

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