Substrate-targeting subunits of the APC/C recognize specific sequence motifs on the proteins that the APC/C ubiquitinates. One motif, the destruction box or D-box, has the consensus sequence

RXXLX[D/E]ΦΦΦXN[N/S]

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#Id: 8199

#Section 3: Genetics, Cellular and Molecular Biology

Lysosomes contain about 40 types of hydrolytic enzymes, All are acid hydrolases, work best at acidic pH including: proteases, nucleases, glycosidases, lipases, phospholipases, phosphatases, and sulfatases.

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#Id: 8533

#Section 3: Genetics, Cellular and Molecular Biology

Rescue 

The change from shrinkage to growth

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#Id: 8353

#Section 3: Genetics, Cellular and Molecular Biology

A second NPF is a large protein complex called WAVE

and requires small GTP-binding protein Rac1.

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#Id: 7930

#Section 3: Genetics, Cellular and Molecular Biology

Secretory pathway

pathway of protein trafficking that flows through the ER

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#Id: 7949

#Section 3: Genetics, Cellular and Molecular Biology

A branched oligosaccharide containing

3 glucose (Glc)

9 mannose (Man)

2 N-acetylglucosamine (GlcNAc)

Glc3Man9(GlcNAc)2