Most common CFTR mutation is a ΔF508 -

Prevents normal transport of CFTR to the plasma membrane by blocking its packaging into COPII vesicles budding from the ER. 

Change the conformation of the cytosolic portion of CFTR so that the signal is unable to bind to Sec24.

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TN-C is the calcium-binding subunit, controls the

position of TM on the surface of an actin filament through the TN-I and TN-T subunits

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#Id: 8895

#Section 3: Genetics, Cellular and Molecular Biology

Monotelic attachment 

only one kinetochore can attach to microtubules

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#Section 2: General Biology

Fe protein 

contains 2 identical subunits (dimer) – nif H

Each subunit has MW of 30 ~ 72 kD.

Each subunit contains an Fe-S cluster (4Fe and 4S2-).

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#Section 2: General Biology

Type 2 T-independent

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#Id: 10358

#Section 2: General Biology

T-dependent response

Recognition of protein antigens and requires the participation of CD4 helper T cells