Two major classes of actin-nucleating proteins:

1. Formins nucleate the assembly of unbranched filaments 

2. Arp2/3 complex nucleates the assembly of branched actin networks

TLS Online TPP Program

#Id: 9211

#Section 3: Genetics, Cellular and Molecular Biology

THE MAGNITUDE OF GENETIC DRIFT

n  = population size

pq=allelic frequency

sp2=variance in allelic frequency among the populations

TLS Online TPP Program

#Id: 9212

#Section 3: Genetics, Cellular and Molecular Biology

Loss of their original diversity per generation

=1/2n

Gain of their original diversity per generation

=1/2n 

Gain or Loss of their original diversity per generation

=1/4n

TLS Online TPP Program

#Id: 9213

#Section 3: Genetics, Cellular and Molecular Biology

Probability of being heterozygote in given population

H = 1 - 1/2N

TLS Online TPP Program

#Id: 9214

#Section 3: Genetics, Cellular and Molecular Biology

Effective population size(Ne)

Effective number of breeding adults in a population.

TLS Online TPP Program

#Id: 9215

#Section 3: Genetics, Cellular and Molecular Biology

Some factor determine Ne

1.Sex ratio.

2.Variation between individual in reproduction success.

3.Fluctuation in population size.

4.The age structure of the population.

5.Mating is random.

TLS Online TPP Program

#Id: 9216

#Section 3: Genetics, Cellular and Molecular Biology

Ne = Male + Female  (when both are equal)

Ne = 4 × n(male) × n(female)/n(male)+n(female) 

(When both unequal Ne is smaller than then sum of both)