TLS Online TPP Program

#Id: 7935

#Section 3: Genetics, Cellular and Molecular Biology

The SRP is a cytosolic ribonucleoprotein particle that transiently binds to both the ER signal sequence in a nascent protein and the large (60S) ribosomal subunit, forming a large complex.

TLS Online TPP Program

#Id: 8515

#Section 3: Genetics, Cellular and Molecular Biology

Kinesin-1 

is regulated by a 

head-to-tail interaction

TLS Online TPP Program

#Id: 8859

#Section 3: Genetics, Cellular and Molecular Biology

During G1, 

cohesins associate with chromosomes by cohesin loading factors Scc2 and Scc4 and unloaded continuously by a cohesin associated complex Pds5 and Wap1 proteins. 

TLS Online TPP Program

#Id: 2246

#Section 3: Genetics, Cellular and Molecular Biology

Some people have an allele called Δ32 at the CCR5 locus in which 32 bp are deleted.

CCR5 that plays a role in inflammatory response. Unfortunately, this protein is also a key to human immunodeficiency virus (HIV) infection. The virus binds to a loop of the CCR5 protein and then enters the cell.

The missing part of the gene codes for the loop in the protein to which the virus attaches. 

TLS Online TPP Program

#Id: 7929

#Section 3: Genetics, Cellular and Molecular Biology

The ER captures selected proteins from the cytosol as they are being synthesized. These are of two types:

Transmembrane proteins

Water-soluble proteins