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At the same time that Cdc25C is being activated, mitotic CDKs and Plk1 phosphorylate Wee1, which targets it for destruction through a phosphobinding SCF protein-ubiquitin ligase. This forms positive feedback loop 2

#Section 3: Genetics, Cellular and Molecular Biology #Steps in cell cycle, regulation and control of cell cycle #Part B Pointers
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#Section 3: Genetics, Cellular and Molecular Biology

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#Section 3: Genetics, Cellular and Molecular Biology

Loop method for inbreeding coefficient
Summation of all possible loop (1/2)n

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#Section 3: Genetics, Cellular and Molecular Biology

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#Section 3: Genetics, Cellular and Molecular Biology

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#Section 3: Genetics, Cellular and Molecular Biology

When inbreeding takes place, the frequency of genotype

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#Section 3: Genetics, Cellular and Molecular Biology

Close inbreeding is harmful because it increases the proportion of homozygotes and thereby boosts the probability that deleterious and lethal recessive alleles.

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