CAUSES OF GENETIC DRIFT

Genetic drift in a small population over multiple generations can significantly affect the composition of a population’s gene pool. 

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The tumor down regulates the expression of class I MHC proteins

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Unassembled or misfolded proteins in the ER are often transported back to the cytosol, where they are degraded in the ubiquitin-proteasome pathway

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Ornithine and citrulline, which are not found in proteins, are intermediates in the biosynthesis of arginine and in the urea cycle.