TLS Online TPP Program

#Question id: 3809


MMR is a highly conserved biological pathway. Several human MMR proteins have been identified based on their homology to E. coli MMR proteins. Match the following

Human

Function

1. MSH2-MSH6

A. DNA mismatch/damage recognition

2. MLH-PMS

B. Molecular matchmaker

3. MutH

C. Strand discrimination

D. Absent in Human


#Section 3: Genetics, Cellular and Molecular Biology
  1. 1A, 2B, 3C 

  2. 1D, 2B, 3C 

  3. 1A, 2D, 3C  

  4. 1B, 2D, 3C

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TLS Online TPP Program

#Question id: 15137

#Section 6: Plant, Animal and Microbial Biotechnology

Most mitochondrial proteins however, are manufactured under the direction of the nucleus. Mitochondria reproduce by 

TLS Online TPP Program

#Question id: 15138

#Section 7: Recombinant DNA technology and Other Tools in Biotechnology

Match the items in group 1 with an appropriate description in group 2.

Group 1Group 2
(P) SWISS PROT(1) derived protein structure database
(Q) Local alignment(2) protein sequence database
(R) CATH(3) GAP
(S) Global alignment(4) Smith–Waterman algorithm

TLS Online TPP Program

#Question id: 15139

#Section 7: Recombinant DNA technology and Other Tools in Biotechnology

Which one of the following is NOT a structure or structurally derived database?

TLS Online TPP Program

#Question id: 15140

#Section 7: Recombinant DNA technology and Other Tools in Biotechnology

Two types of pair-wise sequence alignment of the same hypothetical protein sequence fragments are illustrated in the figure below. Vertical bars between the sequences indicate the presence of identical amino acids. * symbols in Figure Y indicate residues not included in the alignment.





Which one of the following is correct?

TLS Online TPP Program

#Question id: 15141

#Section 7: Recombinant DNA technology and Other Tools in Biotechnology

An alignment of two protein sequences is given below:

Sequence A         A G A A C D E V I G
Sequence B         A G E Y C D A V I G
The similarity score (%) for the above alignment will be:

TLS Online TPP Program

#Question id: 15142

#Section 7: Recombinant DNA technology and Other Tools in Biotechnology

Dot matrix analysis of the amino acid sequences of lambda phage cI (horizontal sequence) and phage P22 c2 (vertical sequence) repressors is shown below. Which one of the following is correct?