TLS Online TPP Program

#Question id: 1704


The single best unique description of the interaction of the αβ T-cell receptor with peptide-MHC is that it:

#Section 2: General Biology
  1. Involves non-covalent forces

  2. Results in T-cell activation

  3. Requires the peptide to be presented by MHC class I

  4. Involves CDR (complementarity-determining region) binding to both peptide and MHC

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TLS Online TPP Program

#Question id: 14134

#Section 7: Recombinant DNA technology and Other Tools in Biotechnology

PAM stands for ___

TLS Online TPP Program

#Question id: 14135

#Section 7: Recombinant DNA technology and Other Tools in Biotechnology

Which of the following statement is correct about PAM matrix? 

TLS Online TPP Program

#Question id: 14136

#Section 7: Recombinant DNA technology and Other Tools in Biotechnology

Which of the following statement is incorrect about global alignment? 
(A) Global alignment is based on the Needleman–Wunsch algorithm.
(B) In Global alignment algorithm, an optimal alignment is obtained over the entire lengths of the two sequences.
(C) It is only suitable for aligning two closely related sequences that are of the same length.
(D) GAP is a web-based pairwise global alignment program.

TLS Online TPP Program

#Question id: 14137

#Section 7: Recombinant DNA technology and Other Tools in Biotechnology

Consider the following alignment of two DNA sequences:
                            AGTAAC
                            AA_ _AC

Assuming an affine gap scoring scheme of an identity matrix for substitution, a gap initiation penalty of 1 and a gap extension penalty of 0.1, the score of the alignment is _________

TLS Online TPP Program

#Question id: 14138

#Section 7: Recombinant DNA technology and Other Tools in Biotechnology

BLAST uses heuristics to align a query sequence with all sequences in a database. 
Reason(R): BLASTX uses protein sequences as queries to search against a protein sequence database.

TLS Online TPP Program

#Question id: 14139

#Section 7: Recombinant DNA technology and Other Tools in Biotechnology

Which of the following statement is incorrect about sequence similarity and sequence identity?