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TLS Online TPP Program

#Id: 10051

The force accompanying the movement of Delta into the signaling cell stretches the Notch protein on the responding cell and allowing access by ADAM 10, which cleaves the Notch extracellular domain

#XL - T Zoology #Delta Notch Signaling #Part B Pointers
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TLS Online TPP Program

#Id: 9083

#XL - T Zoology

Cholera toxin, secreted by Vibrio cholerae in the intestine of an infected person, is a heterodimeric protein (AB). 
TLS Online TPP Program

#Id: 9084

#XL - T Zoology
TLS Online TPP Program

#Id: 9085

#XL - T Zoology

Subunit B recognizes and binds to specific gangliosides on the surface of intestinal epithelial cells and provides a route for subunit A to enter. 
TLS Online TPP Program

#Id: 9086

#XL - T Zoology

A1 associates with ARF6, a small G protein in host cells which are accessible only when ARF6 is in its active (GTP-bound) form. 
TLS Online TPP Program

#Id: 9087

#XL - T Zoology

Association with ARF6 activates A1, which catalyzes the transfer of ADP-ribose from NAD to the critical Arg residue in the P loop of the  subunit of Gαs. 
TLS Online TPP Program

#Id: 9088

#XL - T Zoology