Focal adhesions 

Adhesion type- Cell-matrix

Adhesion receptors- Integrins

Cytoskeletal attachment- Actin filaments

TLS Online TPP Program

#Id: 9653

#XL - T Zoology

Activated dimeric MAP kinase induces transcription of the c-fos gene by directly activating TCF, and indirectly activating SRF.

TLS Online TPP Program

#Id: 9654

#XL - T Zoology

Feedback regulation by MAP Kinase

activated MAP kinase phosphorylates the HER1 on a threonine residue near the juxtamembrane domain. 

TLS Online TPP Program

#Id: 9655

#XL - T Zoology

Feedback regulation by MAP Kinase

Phosphorylation of threonine residue in HER1 decreases the ability of the receptor kinase to become fully active.

TLS Online TPP Program

#Id: 9656

#XL - T Zoology

Feedback regulation by MAP Kinase

Active MAP kinase phosphorylates Raf on multiple sites, reducing its association with Ras.

TLS Online TPP Program

#Id: 9657

#XL - T Zoology

Negative feedback regulation by MAP Kinase

activated MAP kinase triggers an increase in the expression of dual-specificity phosphatases (DUSPs), particularly DUSP6.

TLS Online TPP Program

#Id: 9658

#XL - T Zoology

Hormonal stimulation of GPCR leads to the activation of PLC (IP3/DAG pathway).