Negatively charged amino acids have four ionisations zones

1. 1--------pK1 – charge +1

2. pK1---------pKr charge 0

3. pKr---------pK2 charge -1

4. pK2---------14 charge -2

TLS Online TPP Program

#Id: 8022

#XL - Q Biochemistry

TLS Online TPP Program

#Id: 8540

#XL - Q Biochemistry

Dynein-related transport requires dynactin, that links dynein to its cargo

TLS Online TPP Program

#Id: 8539

#XL - Q Biochemistry

The short (∼20 amino acid) C-terminal tails of both α- and β-tubulin that protrude from the microtubule are enriched in glutamic and aspartic acids, the surface of the microtubule possesses a net negative charge.

TLS Online TPP Program

#Id: 8538

#XL - Q Biochemistry

Microtubules can be stabilized by side-binding microtubule associated proteins (MAPs).

TLS Online TPP Program

#Id: 8537

#XL - Q Biochemistry

Augmin-induced branches help build the spindle during mitosis.

TLS Online TPP Program

#Id: 8536

#XL - Q Biochemistry

Plant cells rely extensively on augmin-dependent microtubule branching nucleation to organize the microtubule cytoskeleton because they lack centrosomes.