Glycine at pH 2.34, where there is an equal mixture of

  the average or net positive charge is 0.5 or +1/2

#Id: 8348

#XL - Q Biochemistry

The major NPF family is characterized by the presence of a region called WCA (WH2, connector, acidic)

#Id: 8347

#XL - Q Biochemistry

To nucleate the assembly of branched actin filaments, Arp2/3 needs to be activated by a nucleation promoting factor (NPF)

#Id: 8346

#XL - Q Biochemistry

Formins are activated by membrane-bound Rho-GTP, a Ras-related small GTPase

#Id: 8345

#XL - Q Biochemistry

#Id: 8343

#XL - Q Biochemistry

formin family members have two adjacent domains:

FH1- rich in proline, landing site for profilin–ATP–G-actin

FH2 - form a dimer and nucleate filament assembly

#Id: 8342

#XL - Q Biochemistry