Most common CFTR mutation is a ΔF508 -

Prevents normal transport of CFTR to the plasma membrane by blocking its packaging into COPII vesicles budding from the ER. 

Change the conformation of the cytosolic portion of CFTR so that the signal is unable to bind to Sec24.

TLS Online TPP Program

#Id: 7357

#XL - T Zoology

TLS Online TPP Program

#Id: 8900

#XL - R Botany

The Aurora protein kinase family members Aurora A and Aurora B and their associated regulatory factors sense kinetochores that are not under tension and sever these microtubule attachments

TLS Online TPP Program

#Id: 10592

#XL - R Botany

II.Non-Vascular plants (Bryophytes)

Haplodiplontic alteration of generation

TLS Online TPP Program

#Id: 9669

#XL - T Zoology

PI-3 kinase was first identified in studies of the 

polyoma virus, a DNA virus

TLS Online TPP Program

#Id: 8522

#XL - Q Biochemistry

Lysine acetylation 

ε-amino group of a specific lysine of α-tubulin

Microtubules are stabilized against breakage (centrioles, basal bodies, & primary cilia)