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TLS Online TPP Program

#Id: 8408

Tropomyosin (TM) is a ropelike molecule, about 40 nm in length, binds to 7 actin subunits in an actin filament.

#XL - Q Biochemistry #Myosin & Muscle Contraction #Part B Pointers
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TLS Online TPP Program

#Id: 9309

#XL - T Zoology

Autosomal recessive mutations in the RPE65 gene are a frequent cause of blindness in children.
TLS Online TPP Program

#Id: 9310

#XL - T Zoology

In the dark, 
membrane potential of a rod cell is about −30 mV (Depolarized state)
Rod cells release neurotransmitters (glutamate) constantly
TLS Online TPP Program

#Id: 9311

#XL - T Zoology
TLS Online TPP Program

#Id: 9312

#XL - T Zoology

Depolarized state of a resting rod cell is due to the presence of a large number of open nonselective ion channels that admit both Na+ & Ca2+ into the cell
TLS Online TPP Program

#Id: 9313

#XL - T Zoology

Nonselective cation channels open in response to binding of the second messenger cGMP (cGMP-gated channels)
TLS Online TPP Program

#Id: 9314

#XL - T Zoology

3 or 4 cGMP molecules must bind to each channel in order to open it; because of this cooperative allosteric interaction, channel opening is very sensitive to small changes in cGMP levels.