Nonphosphorylated CDK bound to one of its cyclin partners has minimal but detectable protein kinase activity in vitro, although it may be essentially inactive in vivo.

TLS Online TPP Program

#Id: 8611

#XL - T Zoology

Nonphosphorylated CDK bound to one of its cyclin partners has minimal but detectable protein kinase activity in vitro, although it may be essentially inactive in vivo.

TLS Online TPP Program

#Id: 8625

#XL - R Botany

Human SCF complexes contain: 

Three core components - Cul1 subunit, RBX1, Skp1 

and a substrate-targeting F-box protein

TLS Online TPP Program

#Id: 8626

#XL - R Botany

RBX1 is a RING finger–containing protein that binds the E2 ubiquitin-conjugating enzyme.

TLS Online TPP Program

#Id: 8627

#XL - R Botany

phosphoserine/threonine-binding F-box protein is Skp2, which uses a series of leucine-rich repeats to bind to target proteins only when they are phosphorylated.

TLS Online TPP Program

#Id: 8628

#XL - R Botany

APC/C consists of 14 core subunits in metazoans and 13 core subunits in yeast.

TLS Online TPP Program

#Id: 8629

#XL - R Botany

APC/C works with substrate-targeting factors called Cdc20 and Cdh1

TLS Online TPP Program

#Id: 8630

#XL - R Botany