The G1 cyclin-CDK complex (Cln3-CDK in yeast) stimulates the formation of G1/S phase cyclin-CDKs, which initiate bud formation, centrosome duplication, and DNA replication.

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#Id: 8637

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The G1 cyclin-CDK complex (Cln3-CDK in yeast) stimulates the formation of G1/S phase cyclin-CDKs, which initiate bud formation, centrosome duplication, and DNA replication.

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#Id: 8905

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Most of the cohesins along the chromosome arms are removed from chromosomes during prophase, mediated by phosphorylation of cohesins by Plk1 & Aurora B kinase.

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#Id: 8906

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#Id: 8907

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Centromere associated cohesins are specifically protected from phosphorylation dependent removal by protein phosphatase 2A

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#Id: 8908

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Phosphatase is recruited to centromeric by the Shugoshin family of proteins

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#Id: 8909

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Separase cleaves centromeric cohesin, triggering the onset of anaphase, releasing the sister chromatids

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#Id: 8910

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Before anaphase Separase is inhibited by the binding of the protein securin and Mitotic CDKs.