Viruses targets endocytic recycling pathway for cell‐to‐cell spread

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#Id: 8893

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Merotelic attachment 

A kinetochore can attach to microtubules emanating from both poles at the same time

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#Id: 8894

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Syntelic attachment 

Both kinetochores of a sister chromatid pair can attach to microtubules from the same pole

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#Id: 8895

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Monotelic attachment 

only one kinetochore can attach to microtubules

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#Id: 8897

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Sensing mechanism used by cells to detect incorrect chromosome attachments is based on tension.

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#Id: 8898

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If Amphitelic attachment occur  Microtubules pull kinetochores; cohesins resist this pulling force. The resulting tension leads to the outer kinetochore component Ndc80 being pulled away from the protein kinase Aurora B

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#Id: 8900

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The Aurora protein kinase family members Aurora A and Aurora B and their associated regulatory factors sense kinetochores that are not under tension and sever these microtubule attachments