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TLS Online TPP Program

#Id: 9629


c-Cbl contains: 
a domain that binds directly to phosphorylated EGF receptors
a RING finger domain, which recruits ubiquitin-conjugating enzymes and mediates transfer of ubiquitin to the receptor

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TLS Online TPP Program

#Id: 349

#XL - R Botany

The oxaloacetate is converted to PEP by phosphoenolpyruvate carboxykinase. This Mg2+ dependent reaction requires GTP as the phosphoryl group donor.

TLS Online TPP Program

#Id: 353

#XL - R Botany

Transketolase requires the cofactor thiamine pyrophosphate (TPP)


TLS Online TPP Program

#Id: 354

#XL - R Botany

Acetyl-CoA and NADH are potent allosteric inhibitors of the enzyme. 


TLS Online TPP Program

#Id: 355

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Acetyl-CoA inhibits the transacetylase component whereas NADH inhibits the dihydrolipoyl dehydrogenase component. 

TLS Online TPP Program

#Id: 356

#XL - R Botany

The reaction catalyzed by citrate synthase is essentially a Claisen condensation, involving a thioester (acetyl-CoA) and a ketone (oxaloacetate)

TLS Online TPP Program

#Id: 359

#XL - R Botany

Eukaryotic cells have two isozymes of aconitase
• The mitochondrial isozyme (convert citrate to isocitrate in the citric acid cycle)
• The cytosolic isozyme 

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