The SH2 domains of PLCγ bind to specific phosphotyrosines on the activated RTKs and cytokine receptors, thus positioning PLCγ close to PIP2.

TLS Online TPP Program

#Id: 8537

#XL - Q Biochemistry

Augmin-induced branches help build the spindle during mitosis.

TLS Online TPP Program

#Id: 8536

#XL - Q Biochemistry

Plant cells rely extensively on augmin-dependent microtubule branching nucleation to organize the microtubule cytoskeleton because they lack centrosomes.

TLS Online TPP Program

#Id: 8535

#XL - Q Biochemistry

Augmin

an 8-subunit protein complex that binds to sites along the microtubule and recruits γ-TuRC, which nucleates a new microtubule to form a microtubule branch.

TLS Online TPP Program

#Id: 8534

#XL - Q Biochemistry

γ-tubulin ring complex (γ-TuRC)

nucleates assembly of a microtubule by forming a template corresponding to the (−) end. 

TLS Online TPP Program

#Id: 8533

#XL - Q Biochemistry

Rescue 

The change from shrinkage to growth

TLS Online TPP Program

#Id: 8532

#XL - Q Biochemistry

Catastrophe 

The change from growth to shrinkage