The cytosolic phosphoserine binding protein 14-3-3 then binds to phosphorylated FOXO3a and sequesters it in the cytosol.

TLS Online TPP Program

#Id: 8189

#XL - Q Biochemistry

C-terminal peroxisomal signal sequences Ser–Lys–Leu (PTS1)

N-terminal peroxisomal signal sequences slightly longer and partially hydrophobic (PTS2)

TLS Online TPP Program

#Id: 9638

#XL - T Zoology

Sos is a GEF that catalyzes conversion of inactive GDP bound Ras to the active GTP-bound form.

TLS Online TPP Program

#Id: 8891

#XL - R Botany

Kinetochores assemble on regions of chromosomal DNA marked by a centromere-specific H3 histone variant called CENP-A.

TLS Online TPP Program

#Id: 8920

#XL - T Zoology

During anaphase, when cyclin B-CDK1 activity is extinguished but Aurora and Polo kinases are still active, Aurora B phosphorylates MKLP1 and displaces the 14-3-3, allowing compact the spindle midzone.

TLS Online TPP Program

#Id: 8176

#XL - Q Biochemistry

SNARE complex is disassembled by ATP-dependent reaction mediated by cytosolic proteins, NSF & α-SNAP