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Mating pathway in the yeast S. cerevisiae, is a MAP kinase cascade which linked to GPCRs.

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Antimicrobial proteins

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Antimicrobial peptide


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Antimicrobial peptides generally are cysteine-rich, cationic, and amphipathic. 
Because of their positive charge and amphipathic nature, they interact with acidic phospholipids in lipid bilayers, forming pores and disrupting the membranes of bacteria, fungi, parasites, and viruses.

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Defensins and cathelicidin LL-37 are secreted constitutively by epithelial cells in many tissues, and are stored as well in neutrophil granules, where they contribute to killing phagocytosed microbes.

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Cellular innate immune responses

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Phagocytosis

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