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Processes That Kill Phagocytosed Microbes
Agents include antimicrobial proteins and peptides, low pH, hydrolytic enzymes including lysozyme and proteases activated by the increasing acidity of the phagolysosomes, and specialized molecules that mediate oxidative attack.

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#XL - Q Biochemistry

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T-dependent response
Recognition of protein antigens and requires the participation of CD4 helper T cells

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Plasma cell decision point


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T-independent response

Type 1 T-independent (TI-1) antigens bind to B cells through both Ig and innate immune receptors. LPS from Gram negative organisms binds to B cells via both mIg and TLR, resulting in signaling from both receptors. 

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