KDC shows Divergent evolution, in which the genes for an enzyme with one substrate specificity give rise, during evolution, to closely related enzymes with different substrate specificities but the same enzymatic mechanism.

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Inflammatory response

Inflammation may be acute (short-term effects)—for example, in response to local tissue damage.

it may be chronic (long term), contributing to conditions such as arthritis, inflammatory bowel disease, cardiovascular disease, and Type 2 diabetes.

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Arachidonic acid and some eicosanoid derivatives

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#Id: 9912

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Cyclooxygenase-2 (COX-2)

Enzyme responsible for the formation from arachidonic acid of prostaglandins and other pro-inflammatory mediators.

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#Id: 9913

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Infectious diseases are disorders caused by organisms — such as bacteria, viruses, fungi or parasites

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#Id: 9914

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Tools against infectious diseases

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Intracellular infections are the most difficult for the immune system to detect and eradicate; these can be divided into membrane-bound and cytosolic, with differing key immune response mediators