Virulence is due to its potent exotoxin, which destroys the underlying tissue and results in heart, liver, and kidney damage, as well as to suffocation following formation of a tough fibrous membrane in the respiratory tract

TLS Online TPP Program

#Id: 8225

#XL - Q Biochemistry

Hurler’s disease- mutation in a structural gene that codes for an individual lysosomal hydrolase.

TLS Online TPP Program

#Id: 8616

#XL - R Botany

Phosphorylation of T14 and Y15 in this G-loop

introduces negative charge that electrostatically interferes with the binding of ATP in the catalytic pocket.

TLS Online TPP Program

#Id: 8879

#XL - R Botany

This combination of two positive feedback loops:

one that activates a CDK1 activator (Cdc25C)

one that inhibits a CDK1 inhibitor (Wee1)

results in the abrupt and irreversible transition from G2 into mitosis.

TLS Online TPP Program

#Id: 9553

#XL - T Zoology

Natural selection was Darwin’s brilliant hypothesis, that accounts for adaptations, features that appear “designed” to fit organisms to their environment.

TLS Online TPP Program

#Id: 10075

#XL - T Zoology

In cultured cells, C → Y mutation in the EC5 domain of CDHR3 increases the cell-surface expression of CDHR3 and the binding and replication of RV-C.