Malaria (Parasitic)

Sporozoites enter the bloodstream by mosquito.

The sporozoites migrate to the liver, where they multiply, transforming liver hepatocytes into giant multinucleate schizonts, which release thousands of merozoites into the bloodstream. 

TLS Online TPP Program

#Id: 10054

#XL - T Zoology

Cleavage by the γ-secretase complex releases the Notch cytosolic segment, which translocates to the nucleus, interacts with a single DNA-binding transcription factor, CSL.

TLS Online TPP Program

#Id: 10055

#XL - T Zoology

Growth factors and EGFs are synthesized as TM proteins, regulated cleavage of the precursor by members of the ADAM protease releases the active molecule into the extracellular space.

TLS Online TPP Program

#Id: 10056

#XL - T Zoology

Cell-adhesion molecules (CAMs) mediate direct cell-cell adhesions.

TLS Online TPP Program

#Id: 10057

#XL - T Zoology

Adhesion receptors mediate cell-matrix adhesions

TLS Online TPP Program

#Id: 10058

#XL - T Zoology

Homophilic Binding 

A CAM on one cell can directly bind to the same kind of CAM on an adjacent cell

TLS Online TPP Program

#Id: 10059

#XL - T Zoology

Heterophilic Binding

A CAM on one cell can directly bind to a different class of CAM on an adjacent cell