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TLS Online TPP Program

#Question id: 644

Enzyme X and Enzyme Y are both involved in monosaccharide metabolism. Enzyme X uses glucose as a substrate while Enzyme Y uses fructose as a substrate. At pH=7.0, Enzyme X has a Vmax of 10 μM/s while Enzyme Y has a Vmax of 20 μM/s. Both enzymes have a Km of 3.0 mM for their respective substrates. Which aspects of its reaction will be changed by Enzyme Y?

#Unit 1. Molecules and their Interaction Relevant to Biology

  1. The activation energy of the reaction and the energy of the product

  2. The rate of the reaction and the energy of the transition state

  3. The equilibrium position of the reaction and the energy of the substrate

  4. The reversibility of the reaction and the energy of the active site

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TLS Online TPP Program

#Question id: 12480

#Unit 7. System Physiology – Animal

A patient’s one remaining kidney has moderate renal artery stenosis that reduces renal artery pressure distal to the stenosis to 85 mm Hg, compared with the normal level of 100 mm Hg. Which of the following is most likely decreased in this patient 2 weeks after the stenosis has occurred, assuming that his diet is unchanged?
TLS Online TPP Program

#Question id: 12390

#Unit 7. System Physiology – Animal

 Which of the following statements is true?
TLS Online TPP Program

#Question id: 12389

#Unit 7. System Physiology – Animal

In a patient with very high levels of aldosterone and otherwise normal kidney function, approximately what percentage of the filtered load of sodium would be reabsorbed by the distal convoluted tubule and collecting duct?
TLS Online TPP Program

#Question id: 12388

#Unit 7. System Physiology – Animal

Which of the following has similar values for both intracellular and interstitial body fluids?
TLS Online TPP Program

#Question id: 12387

#Unit 7. System Physiology – Animal

An elderly patient complains of muscle weakness and lethargy. A urine specimen reveals a Na+ concentration of 600 mmol/L and an osmolarity of 1200 mOsm/L. Additional laboratory tests provide the following information: plasma Na+ concentration = 167 mmol/L, plasma renin activity = 4 ng angiotensin I/ml/hr (normal = 1), plasma antidiuretic hormone (ADH) = 60 pg/ml (normal = 3 pg/ml), and plasma aldosterone = 15 ng/dL (normal = 6 ng/dL). Which of the following is the most likely reason for this patient’s hypernatremia?
TLS Online TPP Program

#Question id: 12386

#Unit 7. System Physiology – Animal

Which of the following changes would you expect to find in a patient who developed acute renal failure after ingesting poisonous mushrooms that caused renal tubular necrosis?