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TLS Online TPP Program

#Question id: 12482

The Rb protein has been called the “master brake” of the cell cycle. How the Rb protein acts as a cell cycle brake?

#Unit 2. Cellular Organization
  1. Rb bound to E2F and function as transcriptional repressors because Rb recruits chromatin-modifying enzymes that promote deacetylation and methylation of specific histone lysines, causing chromatin to assume a condensed, transcriptionally inactive form.
  2. S phase CDKs and mitotic CDKs maintain Rb protein in the phosphorylated state throughout the S, G2, and early M phases.
  3. Rb bound to E2F and promotes ubiquitinylation of E2F and inhibits chromosomal segregation.
  4. Rb bound to E2F and promotes acetylation which prevents unloading of cohesins.
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TLS Online TPP Program

#Question id: 9616

#Unit 9. Diversity of Life Forms

Which mutation should least require realignment of homologous regions of a gene that is common to several related species?
TLS Online TPP Program

#Question id: 9618

#Unit 9. Diversity of Life Forms

Generally, within a lineage, the largest number of shared derived characters should be found among two organisms that are members of the same
TLS Online TPP Program

#Question id: 10324

#Unit 9. Diversity of Life Forms

Which of the following is not true of all horizontally oriented phylogenetic trees, where time advances to the right?
TLS Online TPP Program

#Question id: 11163

#Unit 9. Diversity of Life Forms

The reason that paralogous genes can diverge from each other within the same gene pool, whereas orthologous genes diverge only after gene pools are isolated from each other, is that
TLS Online TPP Program

#Question id: 11162

#Unit 9. Diversity of Life Forms

Which statement represents the best explanation for the observation that the nuclear DNA of wolves and domestic dogs has a very high degree of homology?
TLS Online TPP Program

#Question id: 11161

#Unit 9. Diversity of Life Forms

The lakes of northern Minnesota are home to many similar species of damselflies of the genus Enallagma that have apparently undergone speciation from ancestral stock since the last glacial retreat about 10,000 years ago. Sequencing which of the following would probably be most useful in sorting out evolutionary relationships among these closely related species?