Tay-Sachs disease belongs to the family of lysosomal storage diseases; it is an autosomal recessive neurodegenerative disorder caused by deficiency of the lysosomal enzyme hexosaminidase. The inability to degrade sphingolipids results in the deposition of these lipids in the cells that causes severe mental retardation and death in childhood. The most common mutation in Tay-Sachs disease patients is a 4-base pair insertion in exon 11 of the 14 exons of the hexosaminidase gene. What could be the most likely consequence of this mutation?

#Question id: 5464

#Unit 8. Inheritance Biology

Two varieties of maize averaging AABBCC (200 inch) and aabbcc (80 inch) in height, respectively, are crossed. The F1 progeny is quite uniform averaging 140 inches in height allowed to self fertilization. If height is control by 3 pair of polygene, what is the height of following genotype of F2 plant?

I- AaBBCC     II- aaBbCC       III- aabbCc

#Question id: 5463

#Unit 8. Inheritance Biology

Plants with genotype aabb have seeds that average 1 g in weight, whereas plants with genotype AABB have seeds that average 3.4 g in weight. Plant with genotype aabb is crossed with plant of genotype AABB. If the F1 plants are intercrossed to produced 2/8 proportional of F2 plant having expected seed weight

A  . 1.6        B- 2.8        C-  2.2       D. 1             E . 3.4  

#Question id: 5462

#Unit 8. Inheritance Biology

What was the ratio of F2 generation when red and white kernelled variety of wheat were crossed when 2 QTL control character?

#Question id: 5461

#Unit 8. Inheritance Biology

When two or more nonallelic gene pairs affect the same character in the same way, it is called _______.

#Question id: 5460

#Unit 8. Inheritance Biology

Which of the following describes the dissimilarity in the traits due to the variation in genetic factors?

#Question id: 5459

#Unit 8. Inheritance Biology

Who explained the multifactorial hypothesis?