Tumor-suppressor genes generally encode proteins that in one way or another inhibit cell proliferation. Loss-of-function mutations in one or more of these proliferation inhibitory proteins contribute to the development of many cancers. Prominent among the classes of proteins encoded by tumor-suppressor genes are:

A. Intracellular proteins that regulate or inhibit entry into the cell cycle

B. Receptors or signal transducers for secreted hormones or developmental signals that inhibit cell proliferation

C. Checkpoint pathway proteins that arrest the cell cycle if DNA is damaged

D. Proteins that promote apoptosis

Following genes belongs to the above class-

i. p53

ii. Rb

iii.TGF- β

iv. Caspase 3 and 7

which of the following match is correct?

TLS Online TPP Program

#Question id: 23917

#General Aptitude

Oxygen toxicity (in humans) is caused by:

TLS Online TPP Program

#Question id: 901

#Unit 1. Molecules and their Interaction Relevant to Biology

Proteins with high Tm values are generally stable at

TLS Online TPP Program

#Question id: 5706

#Unit 8. Inheritance Biology

Species A has 2n = 16 chromosomes and species B has 2n = 14. How many chromosomes would be found in an allotriploid of these two species?

TLS Online TPP Program

#Question id: 11755

#Unit 7. System Physiology – Animal

Which of the following solutions when infused intravenously would result in an increase in extracellular fluid volume, a decrease in intracellular fluid volume, and an increase in total body water after osmotic equilibrium?

TLS Online TPP Program

#Question id: 9583

#Unit 6. System Physiology – Plant

 A mechanism known as the Q cycle accounts for most of the observations in which structure and reactions of plastoquinone that operate in,