Following statements are regarding to the apoptosis which is induced by trophic factors.

A. The presence of specific trophic factors (e.g., NGF) leads to activation of their cognate receptor tyrosine kinases (e.g., TrkA) and activation of the PKB pathway.

B. DNA damage or ultraviolet irradiation leads to induction of synthesis of the BH3-only Puma protein. Puma binds to Bak and Bax as well as to Bcl-2, allowing Bak and Bax to form oligomeric pores.

C. Removal of a cell from its substratum disrupts integrin signaling, leading to release of the BH3-only Bim protein from the cytoskeleton.

D. Binding of extracellular death signals, such as tumor necrosis factor and Fas ligand, to their receptors oligomerizes an associated protein (FADD), which in turn triggers the caspase cascade, leading to cell murder by apoptosis.

Which of the following pathway does not belong to the trophic factor inducing apoptotic pathway?

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#Question id: 13147

#Unit 8. Inheritance Biology

A cross was made between pure Blue and long pollen length with white and short pollen length. The F1 were test crossed. The F2 progeny obtained was as follows:

The genetic distance (cM) between flower colour and pollen length is;

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#Question id: 13146

#Unit 8. Inheritance Biology

Two gene A and B  gene distance is 30 m.u. if the frequency of the given gametes is,

i) AaBb=0.70 ii) Aabb=0.30

What will be the correct prediction?

a) Genes a and b are linked in cis

b) A and B gene are independently assort

c) Gene a and b showing incomplete linkage

d)  Genes a and b are linked in trans

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#Question id: 13145

#Unit 8. Inheritance Biology

We can construct a genetic map by considering the recombination frequencies for each pair of genes. The recombination frequency between a and b is 50%, a and c is 50%, and b and c is 20%. What will be the correct prediction about this statements;

a)  Recombination frequency between genes a and b and gene a and c is expected with independent assortment

b) The genes a and b and gene a and c may either be on different chromosomes or be very far apart on the same chromosome;  so we will place them in different linkage groups

c) The gene b and c are linked

d) The gene b and c are unlinked

Which of the following is the correct sequence?

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#Question id: 13005

#Unit 8. Inheritance Biology

50 meiocytes with the genotype AaBb has 5% recombinational frequency in their gametes A and B, then how many meiocytes undergoes to the single crossing over ?

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#Question id: 13004

#Unit 8. Inheritance Biology

If the 120 meiocytes undergoes to the single crossing over then what will be the correct prediction about this ;

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#Question id: 13003

#Unit 8. Inheritance Biology

If 200 meiocytes with AaBb and   80 meiocytes  undergoes to single crossing over between  gene A and B. What will be the chance of crossing over and what is the recombination frequency of the gametes?