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TLS Online TPP Program

#Question id: 1523

Following statements are regarding to the apoptosis which is induced by trophic factors.

A. The presence of specific trophic factors (e.g., NGF) leads to activation of their cognate receptor tyrosine kinases (e.g., TrkA) and activation of the PKB pathway.

B. DNA damage or ultraviolet irradiation leads to induction of synthesis of the BH3-only Puma protein. Puma binds to Bak and Bax as well as to Bcl-2, allowing Bak and Bax to form oligomeric pores.

C. Removal of a cell from its substratum disrupts integrin signaling, leading to release of the BH3-only Bim protein from the cytoskeleton.

D. Binding of extracellular death signals, such as tumor necrosis factor and Fas ligand, to their receptors oligomerizes an associated protein (FADD), which in turn triggers the caspase cascade, leading to cell murder by apoptosis.

Which of the following pathway does not belong to the trophic factor inducing apoptotic pathway?

#Unit 4. Cell Communication and Cell Signaling

  1. A only

  2. B and D

  3. C only

  4.  D only

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TLS Online TPP Program

#Question id: 23555

#Unit 1. Molecules and their Interaction Relevant to Biology

Value education makes a student:
TLS Online TPP Program

#Question id: 3888

#Unit 3. Fundamental Processes

Which of these polymerases does not require a template?
TLS Online TPP Program

#Question id: 23463

#General Aptitude

Statement— Should Indian scientists working abroad be called back to India?
Arguments—
I) Yes. They must serve the motherland first and forget about discoveries, honours, facilities and all.
II) No. We have enough talent; let them stay where they want.
TLS Online TPP Program

#Question id: 13122

#Unit 2. Cellular Organization

Choose the incorrect?
1- COPI vesicles transport proteins from the rough ER to the cis -Golgi; COPII vesicles transport proteins in the reverse s Direction.
2- The KDEL receptor binds more tightly to its ligand ar low pH, and it is thought that the receptor is able to bind KDEL peptides in the cis-Golgi but to release these peptides in the ER because the pH of the Golgi is slightly lower than that of the ER.
3- The KDEL sorting signal is recognized and bound by the KDEL receptor, a transmembrane protein found primarily on small transport vesicles shuttling between the ER and the cis -Golgi and on the cis-Golgi reticulum.
TLS Online TPP Program

#Question id: 26915

#Unit 10. Ecological Principles

Cell walls allow plant cells to build up large internal hydrostatic pressures called