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TLS Online TPP Program

#Question id: 12954

A 55-year-old male patient with hypertension has had his blood pressure reasonably well controlled by administration of a thiazide diuretic. During his last visit (6 months ago) his blood pressure was 130/75 mm Hg and his serum creatinine was 1 mg/100 ml. He has been exercising regularly for the past 2 years, but recently has complained of knee pain and began taking large amounts of a nonsteroidal anti-inflammatory drug. When he arrives at your office, his blood pressure is 155/85 and his serum creatinine is now 2.5 mg/100 ml. Which of the following best explains his increased serum creatinine?

#Unit 7. System Physiology – Animal
  1. Increased efferent arteriolar resistance that reduced GFR
  2. Increased afferent arteriolar resistance that reduced GFR
  3. Increased glomerular capillary filtration coefficient that reduced GFR
  4. Increased angiotensin II formation that decreased GFR
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TLS Online TPP Program

#Question id: 26454

#Unit 3. Fundamental Processes

Which of the following is incorrect related to prokaryotic promoter search
TLS Online TPP Program

#Question id: 26453

#Unit 3. Fundamental Processes

Some of the sigma subunit of E. coli and function is given, Choose which of the following is incorrectly matched
TLS Online TPP Program

#Question id: 26452

#Unit 3. Fundamental Processes

Holoenzyme shows highest affinity at
TLS Online TPP Program

#Question id: 26451

#Unit 3. Fundamental Processes

Which of the following characteristics of sigma affect non specific binding of the core
TLS Online TPP Program

#Question id: 26450

#Unit 3. Fundamental Processes

Which of the following statements is true regarding bacterial RNA polymerase   
a. Core enzyme can efficiently transcribe both intact and nicked DNA 
b. Sigma destabilizes nonspecifically bound core 
c. Holoenzyme bind tightly to DNA 
d. Higher disassociation rate at lower temperature 
e. Most of the cellular sigma are house keeping gene
TLS Online TPP Program

#Question id: 26449

#Unit 3. Fundamental Processes

Ability of core and holoenzyme to transcribe DNAs differs, so choose which of the following is correct
a.With  subunit, the holoenzyme worked equally well on both intact as well as nicked types of DNA
b.With  subunit, the holoenzyme worked unequally on both intact as well as nicked types of DNA
c.Core subunit α2ββσ can not perform polymerization on to the intact DNA while perform some of the activity on to the nicked DNA
d.Core subunit α2ββσ can not perform polymerization on to the intact DNA AS WELL AS  to the nicked DNA