TLS Online TPP Program

#Question id: 10771


What is penetrance?
A- % of individuals having phenotype according to their genotype.
B- Penetrance refers to the likelihood that a clinical condition will occur when a particular genotype is absent.
C- 100% expressivity always gives 100% penetrance.
which one of the correct combination-

#Unit 8. Inheritance Biology
  1. A and B
  2. A and C
  3. Only A
  4. all are correct
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TLS Online TPP Program

#Question id: 15155

#Unit 8. Inheritance Biology

In this problem we will explore some of the many ways that mutations in two different genes can interact to produce different Mendelian ratios. Consider a hypothetical insect species that has red eyes. Imagine mutations in two different unlinked genes that can, in certain combinations, block the formation of red eye pigment yielding mutants with white eyes. In principle, there are two different possible arrangements for two biochemical steps responsible for the formation of red eye pigment. The two genes might act in series such that a mutation in either gene would block the formation of red pigment. Alternatively, the two genes could act in parallel such that mutations in both genes would be required to block the formation of red pigment.

Further complexity arises from the possibility that mutations in either gene that lead to a block in enzymatic activity could be either dominant or recessive. If the crosses between a wild type insect with red eyes and a true breeding white eyed strain with mutations in both genes. Such considerations yield the Pathways in parallel with dominant mutations in both genes, determine the phenotype of the F1 progeny and the expected phenotypic ratio of red to white eyed insects in the F2.

TLS Online TPP Program

#Question id: 15303

#Unit 4. Cell Communication and Cell Signaling

Neurofibromatosis, a benign tumor of the sheath cells that surround nerves, is caused by
a.  Loss of both alleles of NF1
b.  Mutation in RAS GAP-type protein
c.  A single mutant NF1 allele
d.  Mutation in SRC protein

TLS Online TPP Program

#Question id: 10943

#Unit 7. System Physiology – Animal

An 8-year-old male is frequently coming to the clinic for persistent skin infections that do not heal within a normal time frame. He had a normal recovery from the measles. Checking his antibodies following immunizations yielded normal antibody responses. A defect in which of the following cells would most like be the cause of the continual infections?

TLS Online TPP Program

#Question id: 15725

#Unit 11. Evolution and Behavior

Alfred Russel Wallace (1823–1913), who was collecting specimens in the Malay Archipelago, had independently conceived that

TLS Online TPP Program

#Question id: 10451

#Unit 6. System Physiology – Plant

Which induction is responsible for “uncages” the kinase domain of phototropin and leads to autophosphorylation