A cross is made between an Hfr that is met+ thi+ pur+ and an F-that is met- thi- pur-. Interrupted mating studies show that met+ enters the recipient last, so met+ recombinants are selected on a medium containing supplements that satisfy only the pur and thi requirements.  These recombinants are tested for the presence of the thi+ and pur+ alleles. The following numbers of individuals are found for each genotype:

A) Gene Order	I	Thi Pur  Met
	II	Pur  Met  Thi
	III	Pur   Thi  Met
B) Distance between Pur and Thi	IV	15.4 map unit
	V	1.8 map unit

What is the following correct combination?

#Question id: 1252

#Unit 4. Cell Communication and Cell Signaling

 Following statements are regarding to the phosphoinositide signaling pathway.

A. Many RTKs and cytokine receptors can initiate the IP3/ DAG signaling pathway by activating phospholipase Cβ (PLCβ), a different PLC isoform.

B. Activated RTKs and cytokine receptors also can initiate another phosphoinositide pathway by binding a PI-3 kinase, thereby allowing the enzyme access to its membrane-bound phosphoinositide substrates, which then become phosphorylated at the 3 position.

C. Protein kinase B (PKB) becomes partially activated by binding to PI 3-phosphates with its PH domain.

D. Full activation of PKB requires phosphorylation by the kinase PDK1, which is also recruited to the membrane by binding to PI 3-kinase, and by a second kinase, PDK2.

Which of the following combination is incorrect?

#Question id: 23347

#Unit 1. Molecules and their Interaction Relevant to Biology

#Question id: 14486

#Unit 13. Methods in Biology

#Question id: 12048

#Unit 7. System Physiology – Animal

#Question id: 10574

#Unit 10. Ecological Principles