Which of the following human diseases is associated with defects in nucleotide excision repair?

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#Question id: 1528

#Unit 4. Cell Communication and Cell Signaling

Mutation of p53 is described as a dominant-negative mutation. Which of the following statement is correct regarding to the mechanism by which this mutation causes the dominant-negative phenotype?

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#Question id: 12481

#Unit 2. Cellular Organization

Following statements are regarding to Kinetochore-microtubule interaction in S. cerevisiae.

A. In the simple kinetochore of S. cerevisiae, a protein complex called CBF3 associates with specialized, centromere-specific form of histone H3, called CENP-A.

B. The Ndc80 complexes initially make lateral interactions with a spindle microtubule and subsequently interact with a Dam1 complex, which forms a ring around the end of the microtubule. This interaction results in an end-on attachment of the centromere to the

spindle microtubule.

C. Microtubules that “capture” kinetochores are selectively stabilized by a reduction in the rate of catastrophes, which increases the chance that the attachment will persist.

D. With the two kinetochores attached to opposite poles, the duplicated chromosome is now under tension, being pulled in both directions by the one sets of kinetochore microtubules.

Which of the following combinations is correct?

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#Question id: 1017

#Unit 4. Cell Communication and Cell Signaling

The outbreak of measles within the last few years was due to

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#Question id: 5691

#Unit 8. Inheritance Biology

Which of the following most accurately explains the cause for the abnormal numbers of chromosomes during human reproduction that can result in Down syndrome, Turner’s syndrome, or Klinefelter’s syndrome?

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#Question id: 102

#Unit 1. Molecules and their Interaction Relevant to Biology

 The structure of a disaccharide is shown below. Which statement is correct about following structure?