A researcher found a method she could use to manipulate and quantify phosphorylation and methylation in embryonic cells in culture. One of her colleagues suggested she try increased methylation of cytosine (C) nucleotides in the DNA of promoters of a mammalian system. Which of the following results would she most likely see?

TLS Online TPP Program

#Question id: 15009

#SCPH12 I Genetics

A mutation in which most of the protein coding sequence of the gene is removed is most likely to be which type of allele?

TLS Online TPP Program

#Question id: 15010

#SCPH01 Biochemistry

The phenomenon where half the "normal" level of functional protein is not enough to generate a normal phenotype is called haploinsufficiency. Which of the following situations demonstrates haploinsufficiency?

TLS Online TPP Program

#Question id: 15010

#SCPH12 I Genetics

The phenomenon where half the "normal" level of functional protein is not enough to generate a normal phenotype is called haploinsufficiency. Which of the following situations demonstrates haploinsufficiency?

TLS Online TPP Program

#Question id: 15011

#SCPH01 Biochemistry

Which of the following statements about a lethal allele is NOT correct?

TLS Online TPP Program

#Question id: 15011

#SCPH12 I Genetics

Which of the following statements about a lethal allele is NOT correct?

TLS Online TPP Program

#Question id: 15138

#SCPH01 Biochemistry

Match the items in group 1 with an appropriate description in group 2.

Group 1                                                                Group 2

(P) SWISS PROT                                 (1) derived protein structure database 

(Q) Local alignment                          (2) protein sequence database

(R) CATH                                             (3) GAP

(S) Global alignment                        (4) Smith–Waterman algorithm