TLS Online TPP Program

#Question id: 5131


Differentiated cells express the genes and proteins characteristic of their final identity in the adult, and that identity can be altered only under special circumstances. How does the concept of differentiation, as described here, differ from the concept of determination?

#SCPH01 Biochemistry
  1. Determined cells have begun to differentiate, but are not fully differentiated.

  2. Determined cells are embryonic cells that will give rise to all the cell types of the adult organism, but have not yet begun to express the genes and proteins characteristic of their final fates.

  3. Determined cells will continue to follow their fate if grafted into a different place in a host embryo, even though they do not yet express the genes and proteins characteristic of their final fate.

  4. Determined cells are embryonic cells that will form certain cell types and structures if development is allowed to proceed normally, but will alter their development in response to their location if transplanted to a different place in a host embryo.

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TLS Online TPP Program

#Question id: 7764

#SCPH06 I Botany

Cellular senescence may have evolved to protect organisms against cancer. Instead of dividing out of control, the cells die. Cellular senescence appears to be regulated by several tumor suppressor genes, especially p53.what is the most appropriate reason behind this,

1) Transcription factor p53 is thought to suppress tumorigenesis by causing cell arrest and senescence in response to short telomeres, DNA damage, and viral or external signals to divide

2) This factor can stop the cell cycle, cause cellular senescence in rapidly dividing cells, instruct genes to initiate cellular apoptosis, and activate DNA repair enzymes.

3) Induction of apoptosis or cellular senescence by p53 always beneficial.

TLS Online TPP Program

#Question id: 7764

#SCPH28 | Zoology

Cellular senescence may have evolved to protect organisms against cancer. Instead of dividing out of control, the cells die. Cellular senescence appears to be regulated by several tumor suppressor genes, especially p53.what is the most appropriate reason behind this,

1) Transcription factor p53 is thought to suppress tumorigenesis by causing cell arrest and senescence in response to short telomeres, DNA damage, and viral or external signals to divide

2) This factor can stop the cell cycle, cause cellular senescence in rapidly dividing cells, instruct genes to initiate cellular apoptosis, and activate DNA repair enzymes.

3) Induction of apoptosis or cellular senescence by p53 always beneficial.

TLS Online TPP Program

#Question id: 7765

#SCPH01 Biochemistry

The enzyme complex or gene that maintains telomere integrity is________, which acts as an antisenescence complex. Mice and humans with its deficiencies age prematurely (Mitchell et al. 1999). Overexpressing or reactivating it in senescent cells extends longevity in mice without increasing cancer,

TLS Online TPP Program

#Question id: 7765

#I Life Science/ Life Sciences Group – I-V

The enzyme complex or gene that maintains telomere integrity is________, which acts as an antisenescence complex. Mice and humans with its deficiencies age prematurely (Mitchell et al. 1999). Overexpressing or reactivating it in senescent cells extends longevity in mice without increasing cancer,

TLS Online TPP Program

#Question id: 7765

#SCPH06 I Botany

The enzyme complex or gene that maintains telomere integrity is________, which acts as an antisenescence complex. Mice and humans with its deficiencies age prematurely (Mitchell et al. 1999). Overexpressing or reactivating it in senescent cells extends longevity in mice without increasing cancer,

TLS Online TPP Program

#Question id: 7765

#SCPH28 | Zoology

The enzyme complex or gene that maintains telomere integrity is________, which acts as an antisenescence complex. Mice and humans with its deficiencies age prematurely (Mitchell et al. 1999). Overexpressing or reactivating it in senescent cells extends longevity in mice without increasing cancer,