The second phase of T-cell development

1.Positive selection: Selection for those cells whose T-cell receptors engage self-MHC.

2.Negative selection: Selection against those cells whose T-cell receptors bind too strongly to self-peptide/MHC combinations.

3.Lineage commitment: Commitment of thymocytes to effector cell lineages, including CD4 helper or CD8 cytotoxic populations

TLS Online TPP Program

#Id: 7801

#Unit 2. Cellular Organization

An RNA helicase (Dbp5) located on the cytoplasmic side of the NPC removes NXF1 and NXT1 from the mRNA in a reaction that is powered by ATP hydrolysis.

TLS Online TPP Program

#Id: 688

#Unit 3. Fundamental Processes

Telomeres form a looped structure in the cell called as t-loop

TLS Online TPP Program

#Id: 743

#Unit 3. Fundamental Processes

TLS Online TPP Program

#Id: 8550

#Unit 1. Molecules and their Interaction Relevant to Biology

diisopropylphosphofluoridate, reacts with a serine OH group in the active site of esterases such as acetylcholinesterase/chymotrypsin, whilst the organomercury compound p-hydroxymercuribenzoate reacts with a cysteine group, in both cases resulting in covalent bond formation and enzyme inhibition.

TLS Online TPP Program

#Id: 1253

#Unit 7. System Physiology – Animal

ADH is the major hormone concerned with regulation of body fluid osmolarity.